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Dialysis ? - (Feb/06/2008 )

Hi Guys
Can dialysis be use to exchange the buffer ? I want to exchange the buffer of my protein from the sod phos. to hepes buffer. sample vol is 3 ml. For how long we should dialyze it and also how many changes we should do ??

Thanks

-veerubiotech-

QUOTE (veerubiotech @ Feb 6 2008, 05:36 PM)
Hi Guys
Can dialysis be use to exchange the buffer ? I want to exchange the buffer of my protein from the sod phos. to hepes buffer. sample vol is 3 ml. For how long we should dialyze it and also how many changes we should do ??

Thanks

Yes, dialysis is used to exchange buffer

3 changes of 500ml buffer.

1st buffer for 6 hr
2nd buffer overnight
3rd buffer 4-6hr.

Hope this may help.

-Minnie Mouse-