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How to make a tetracycline solution - (Mar/25/2005 )

I am making at 5 mg/mL soln of Tetracycline, and am using EtOH per our most recent Molecular Cloning manual...but I am having trouble getting all of the solid dissolved. Should I be using 70 % ETOH? Any thoughts/suggestions would be appreciated!!

-slapolla-

Ive made some Tet sol. a couple of times....be sure to use an analytical balance, and dissolve it in absolute ethanol (100%)....and shake it up like theres no tomorrow...itll take a while but it will go into solution...
Do not autoclave...its ready for use....
Cheers





QUOTE (slapolla @ Mar 25 2005, 10:40 AM)
I am making at 5 mg/mL soln of Tetracycline, and am using EtOH per our most recent Molecular Cloning manual...but I am having trouble getting all of the solid dissolved. Should I be using 70 % ETOH? Any thoughts/suggestions would be appreciated!!

-matiascs-

i agree with matiascs. I do the same
chandima

-chandima-

People,

Err... How do we know when to use water or ethanol? We have so much stocks here that I have yet to prepare any antibiotic solutions.

-dreamchaser_jc-

QUOTE (dreamchaser_jc @ Jan 29 2009, 09:54 AM)
People,

Err... How do we know when to use water or ethanol? We have so much stocks here that I have yet to prepare any antibiotic solutions.


you use that in which it is soluble and stable and will not interfere with your purpose.

-mdfenko-

QUOTE (mdfenko @ Jan 30 2009, 12:53 AM)
QUOTE (dreamchaser_jc @ Jan 29 2009, 09:54 AM)
People,

Err... How do we know when to use water or ethanol? We have so much stocks here that I have yet to prepare any antibiotic solutions.


you use that in which it is soluble and stable and will not interfere with your purpose.


Alright, got it!

-dreamchaser_jc-