siRNA in embryo - (Feb/13/2005 )

I am trying to silence the gene by microinjecting the naked siRNA in the mouse embryo....................does anybody has any experience in it?????????

hi

maybe you can have a look at this articles :

http://www.ncbi.nlm.nih.gov/entrez/query.f...t_uids=15039944
http://www.publish.csiro.au/nid/44/paper/RDv16n1Ab250.htm

the database of qiagen shows informations about transfection in embryo :

http://www1.qiagen.com/Transfection/CellLi...age=2&ShowAll=1

Hope that helps you

please keep us informed