Problems with DMSO,Salt out! - (Aug/22/2008 )

Hello,
I am working on noscapine which is an alkaloid compound.according to the papars I have read,I should solve it in DMSO.But when I want to dilute my DMSO stock solution with water the compound precipitates
I tried medium with and without serum but It made no difference.
Any Ideas?
Please help me
Thanks in advance
Arash

-Acute-

perhaps diluted acid like HCl would help.

-genehunter-1-

The Merck Index will list the solubility of most compounds in a variety of solvents and conditions. I agree that dissolving alkaloids in a slightly acid water often works, and is definitely worth a try.

-phage434-

Not sure if it's "salting out" - are you adding salt?

Suggest you contact the authors of papers you cited - bet they'd have an answer.

-jorge1907-

by salt I meant anything that is solved in DMSO...
I donot know if alkaloids are stable in the soluble acids or not?

-Acute-