demonstrating combinatorial effects.... - any ideas? please help! thanks... (Jun/11/2008 )

Hi, I have made a device for cell assay, and I want to demosntrate the combined effect of 2 or 3 compounds on cells.
I was thinking of either

-treat cells with hydrogen peroxide and some other molecules that can reduce the effect of hydrogen peroxide...? any suggestions on what molecules i can use?
or
-treat cells with non-toxic level of sapnonin and some other toxins and see if saponin can enhance the effect of that toxin...

any suggestions on what compounds i can use ..or any other simple experiments i can try to show the combintorial effects? thanks alot!

-liumaikuh-

Sounds like a homework problem or you aren't explaining yourself well.

To reduce the effects of H2O2, add a PARP inhibitor.

-rosewater-

QUOTE (rosewater @ Jun 11 2008, 05:27 PM)

Sounds like a homework problem or you aren't explaining yourself well.

To reduce the effects of H2O2, add a PARP inhibitor.

Thanks,
Can you give me the link of the paper that talks about PARP inhibitor treatment and reduction of H2O2 effect?

-liumaikuh-

Here's one, but really, you can search pubmed as easily as the rest of us.

J Biol Chem. 2005 Oct 21;280(42):35767-75.

-rosewater-

QUOTE (liumaikuh @ Jun 11 2008, 01:18 PM)

saponin makes cells leaky: there it will be toxic at higher concentrations...

-The Bearer-