Can RNAi be used for silencing of non-coding RNAs? - (May/26/2008 )
I was just curious to know
-Papo Chulo-
QUOTE (Papo Chulo @ May 26 2008, 04:41 AM)
I was just curious to know 

'm curious too.

-cellcounter-
Yes.
Since the siRNA target any rna, you could knockdown non-coding RNAs.
-Madrius-
Yes, it is possible. Check this paper Specific and potent RNAi in the nucleus of human cells
-pcrman-
Great! Thanks. I'm doing this theoretical laboratory project where I have to target human telomerase as a cancer therapy. TERC, prepare for silencing
-Papo Chulo-
QUOTE (Papo Chulo @ May 26 2008, 12:01 PM)
Great! Thanks. I'm doing this theoretical laboratory project where I have to target human telomerase as a cancer therapy. TERC, prepare for silencing 

Theoretical?


-cellcounter-