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Transcription Factors - (Feb/25/2008 )

Hi all, i would like to ask is there any websites or ways that i can identify transcription factors of a gene, preferably for chick (gallus gallus)

Thanks all in advance! laugh.gif

-gregsanders-

QUOTE (gregsanders @ Feb 25 2008, 01:25 PM)
Hi all, i would like to ask is there any websites or ways that i can identify transcription factors of a gene, preferably for chick (gallus gallus)

Thanks all in advance! laugh.gif


Do you mean you want to identify transcription factors that may bind to your gene of interest? I have used Transfact (?) at www.gene-regulation.com (or something like that). Not sure if you can enter chick sequences though. Good luck!

-Clare-

If you're looking for previously described transcription factors then use any science search engine for articles on the subject.
If you're looking for new ones, I think that at most you can find some software that may predict possible interactons between a certain sequence and a certain protein. None of this is valid unless confirmed in the lab though.
If, even more, you want to screen a full genome (or close) to search for TFs that bind to a sequence of yours, you may be asking for too much tongue.gif At least I've never heard of any software that does this...

EDIT: apparently Clare knows a software that may work for this kind of stuff. I've learned something today biggrin.gif

-Ambrósio-

QUOTE (Clare @ Feb 25 2008, 09:59 PM)
QUOTE (gregsanders @ Feb 25 2008, 01:25 PM)
Hi all, i would like to ask is there any websites or ways that i can identify transcription factors of a gene, preferably for chick (gallus gallus)

Thanks all in advance! laugh.gif


Do you mean you want to identify transcription factors that may bind to your gene of interest? I have used Transfact (?) at www.gene-regulation.com (or something like that). Not sure if you can enter chick sequences though. Good luck!



Ah yes yes! thanks for your help

-gregsanders-

QUOTE (Ambrósio @ Feb 25 2008, 10:02 PM)
If you're looking for previously described transcription factors then use any science search engine for articles on the subject.
If you're looking for new ones, I think that at most you can find some software that may predict possible interactons between a certain sequence and a certain protein. None of this is valid unless confirmed in the lab though.
If, even more, you want to screen a full genome (or close) to search for TFs that bind to a sequence of yours, you may be asking for too much tongue.gif At least I've never heard of any software that does this...

EDIT: apparently Clare knows a software that may work for this kind of stuff. I've learned something today biggrin.gif



yeap, that goes for me too, guess we all learn something everyday - apparently it always is the case for science students dry.gif

-gregsanders-