Are these the same things? - (Oct/26/2007 )

Hi there,

Is "amyloid precursor protein" and "amyloid Beta protein" also "Beta-amyloid" all mean the same thing?

Thanks in advance,
b_06er

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This is how I understand it anyway, amyloid precursor protein is the precurser to amyloid beta protein- its cleaved and the cleaved fragment is called amyloid beta protein, cleaved by something (I can't remember off the top of my head).


But I think beta-amyloid and amyloid beta can be interchanged. If I'm wrong I hope someone knows the real answer

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lost in the lab is correct. the proteases responsible for the cleavage are secretases (beta and gamma make amyloid beta protein and alpha prevents it).

if you are interested, check this wiki site: wiki: secretase

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Cheers for that- its been ages since I've read anything about amyloid- my memory is getting rusty, I'm glad it still remembers some things though

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