SSA and NHEJ ...what do they mean? - (Sep/03/2007 )

helloo!!

recently, i read a paper about DNA double strand break repair, I try to distinguish between `single-strand annealing[SSA] ` & `non-homologous end joining [NHEJ] `... but still couldn`t comprehend....

I mean, if for SSA, how does DNA anneal? by overhangs or by blunt-ends DNA strand?

i really appreciate anyone who could help....help me understand my paper better....

NHEJ: http://en.wikipedia.org/wiki/Non-homologous_end_joining

SSA: http://www.bio.brandeis.edu/haberlab/jehsite/ssa.html


i hope these sites will help you understand.

yes, thanks!

the one with pictures helps a lot, i easily get confused when description is too long...