Universal probe library probes.... - (Jul/23/2007 )
QUOTE (Senior_Scientist @ Jul 14 2008, 11:18 PM)
-The LC480 is more sensitive in detection therefor it works a bit better than AB instruments (especially the older generation of the 7x00s). However you can improve your assays with their FastStart Universal Probe Master (Rox) when using AB or Bio-Rad instruments (and others).
Soory for the off-topic.
Sensitivity of both platforms approach the theoretical limit. Thus I cannot see how LC480 could outperform 7x00 series with respect to that.
-Pallas-
Sensitivity of both platforms approach the theoretical limit. Thus I cannot see how LC480 could outperform 7x00 series with respect to that.
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In this case I spoke about sensitivity of the optical system: and the LC480 definitely has the best optic (that's why they do not need a rox reference dye) including filters, optic alignment and light source (insensitive laser when using dyes other than FAM). But of course for typical fam assays from abi the sensitivity of the systems as a whole may be almost the same 
-Senior_Scientist-
QUOTE (Senior_Scientist @ Jul 17 2008, 10:14 PM)
In this case I spoke about sensitivity of the optical system: and the LC480 definitely has the best optic (that's why they do not need a rox reference dye) including filters, optic alignment and light source (insensitive laser when using dyes other than FAM). But of course for typical fam assays from abi the sensitivity of the systems as a whole may be almost the same
Thanks for the reply!
I also read your post on another topic, where you also compare LC480 with AB platforms. Really appreciate your input!
-Pallas-