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silver colloids - how do they act? (May/15/2007 )

Hi there, maybe I'm a bit off-topic; in this case sorry for that, I'm just curious. A friend of mine has a stomach problem with Helicobacter. the doctors suggested antibiotics but he still feels he is not ok. He heard about these silver colloids as good antibiotics. He asked me if I know it works or not - but in fact I don't even know how they act. I found some papers on Pubmed but the fulltext is mostly not available so if you have some infos or experiences, pls share with me.
Cheers

-egerecske-

QUOTE (egerecske @ May 15 2007, 11:32 AM)
Hi there, maybe I'm a bit off-topic; in this case sorry for that, I'm just curious. A friend of mine has a stomach problem with Helicobacter. the doctors suggested antibiotics but he still feels he is not ok. He heard about these silver colloids as good antibiotics. He asked me if I know it works or not - but in fact I don't even know how they act. I found some papers on Pubmed but the fulltext is mostly not available so if you have some infos or experiences, pls share with me.
Cheers


the triple therapy against Hp is the standard, and succeeds in more than 90%; if there is no success the cocktail of antibiotics should be changed; I have never heard that silver colloids should work better than antibiotics; with silver you may histochemicallystain the nucleus of gastric mucosal cells

-The Bearer-

Cool, silver stained nuclei in the stomach - I would really like to hear what the pathologist says after an autopsy and histology ... probably, he would blaim his assistant.

Silver colloids are ssurely nothing one should try to eradicate helicobacter pylori with. There are two triple therapy schemes (french and italian) which are very effective. And, the only way to prove inefficiency is a gastroscopy. If he just still has problems with his stomach, it could be something different (e.g. gaster irritabile).

-krümelmonster-

might make an interesting case of nano particle poisoning.

I feel it is unlikely that the silver colloid would remain long enough in the stomach to do H. pylori, harm. More likely it will react in interesting ways with stomach acids and do interesting things once it gets into cells.

-perneseblue-

QUOTE (krümelmonster @ May 15 2007, 05:51 PM)
Cool, silver stained nuclei in the stomach - I would really like to hear what the pathologist says after an autopsy and histology ... probably, he would blaim his assistant.

Silver colloids are ssurely nothing one should try to eradicate helicobacter pylori with. There are two triple therapy schemes (french and italian) which are very effective. And, the only way to prove inefficiency is a gastroscopy. If he just still has problems with his stomach, it could be something different (e.g. gaster irritabile).


for those aficionados who may want to learn more about histological silver-stain method, I suggest the following example
http://gut.bmj.com/cgi/content/full/44/6/789 where you will find silver stained nuclei in gastric mucosa; you may find other examples as the method is often used.

In general, silver-staining of tissues is useful for the detection of nucleolar organizer regions (AgNOR), and to estimate, especially in the case of malignancy, modifications in NOR on the one hand, and proliferation or altered metabolism on the other hand.

The following article provides a good introduction in the field of AgNOR:
http://www.ncbi.nlm.nih.gov/entrez/query.f...p;dopt=Abstract

-The Bearer-