ZVAD.fmk-how does it work - (Oct/02/2006 )

Hi,

does anyone know where i can find out exactly how the pan-caspase inhibitor ZVAD.fmk works?
I know it inhibits caspases but i need to knw exactly how it does this for my thesis...Ta!!!

xxx

-fourthyeardesperado-

QUOTE (fourthyeardesperado @ Oct 2 2006, 05:42 PM)

Hi,

does anyone know where i can find out exactly how the pan-caspase inhibitor ZVAD.fmk works?
I know it inhibits caspases but i need to knw exactly how it does this for my thesis...Ta!!!

xxx

Hi,
Here is the original paper where they show how the inhibiotr works

Elizabeth A. SLEE, Gerald M. COHEN
1996, 315, 21-24, Biocem. J

I hope this helps,
Cheers

-suheda-