collagen or gelatin coating: do they perform differently? - or do you really get what you are paying for? (Sep/21/2006 )

Hi, guys:

I guess there must be a reason why people would spend $$$ on collagen over cheap gelatin. But seriously, has anyone experienced difference in cell growth on collagen vs with gelatin coated surface ?

I think gelatin is somehow crude and not well defined for the composition of collagen types or any other components; so, there might be differences in gelatin quality between providers and even charges; if there is no need to exactly define the coat, to say "collagen I" or "collagen IV", why not a trial with gelatin...however, I would look for effects of different charges

My PI says that gelatin is used to help cells adhere better but collagen is used for better cell growth and especially in neurons cultures for better neurite outgrowth.

But I have never compared them.