How QBI SP163 translational enhancer works? - (May/25/2006 )

Hi everybody:

Who have any idea on how QBI SP163 translational enhancer from pcDNA4/HisMax works?

Thanks in advance!

[quote name='Cinba' date='May 25 2006, 11:28 PM' post='53041']
Hi everybody:

Who have any idea on how QBI SP163 translational enhancer from pcDNA4/HisMax works?

Thanks in advance!
[/quote

Hi:

I feel so regretful that no one can tell me how QBI SP163 translational enhancer works?

see
The QBI SP163 translational enhancer is derived from the 5'-untranslated region of the vascular endothelial growth factor gene and is claimed to increase expression levels two- to fivefold compared with promoter alone.
http://www.patentstorm.us/patents/6653132/description.html
United States Patent 6653132
Stein et al., 1998 I. Stein, A. Itin, P. Einat, R. Skaliter, Z. Grossman and E. Keshet, Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia, Mol. Cell. Biol. 18 (1998), p. 3112.