Antibodies of different class in blood of different species. - (Feb/11/2006 )

Hi,
Does anyone have information on contents of antibodies of different class (IgG, IgE, IgM etc.) in blood of different species (humans, rabbits, mice, rats etc.)? Best would be m/v (mg/L etc.) or % of total protein (or globulin).

Regards,
Chris

Hello,

contents of antibodies of different class (IgG, IgE, IgM etc.) in blood of humans in % of total serum antibodies.

IgG makes up approximately 80% of the serum antibodies.
IgA makes up approximately 6% of the serum antibodies.
IgD makes up approximately 0.2% of the serum antibodies.
IgE makes up about 0.002% of the serum antibodies.
IgM makes up approximately 13% of the serum antibodies.

for further details:

http://www.cat.cc.md.us/courses/bio141/lec...y/antibody.html

good luck

Thank you!

I just found values for human:
IgG - 1250 (700-1750) mg / 100 ml
IgA - 210 (90-450) mg / 100 ml
IgM - 140 (65-260) mg / 100 ml
IgD - 3 (0,3-40,0) mg / 100 ml
IgE - 0,03 (0,006-0,6) mg / 100 ml

Values for rabbit would be even more useful since I use them, not humans, as source of antibodies...

J. Dairy Sci. 87:1641-1674
Nomenclature of the Proteins of Cows' Milk - Sixth Revision
H.M. Farrel et al.
abstract
full text (html)
full text (pdf)

page 1665, table 6):

Rabbit --- IgG --- (serum) 5 to 10 mg/mL
IgA --- 0.01
IgM --- 0.01

Regards,
Chris