PAM or BLOSUM? - (Dec/19/2005 )
Hi, I'm inexpert in bioinformatics and I need to make a multiple alignment of aminoacidic sequences.
I use ClustalX 1.81 but I don't know if is better to use PAM matrix or BLOSUM matrix.
Can anyone help me?
And also I'd like to know how the Gonnet matrix works.... Thank you in anticipate 
-biotechgirl-
QUOTE (biotechgirl @ Dec 19 2005, 05:21 AM)
Hi, I'm inexpert in bioinformatics and I need to make a multiple alignment of aminoacidic sequences.
I use ClustalX 1.81 but I don't know if is better to use PAM matrix or BLOSUM matrix.
Can anyone help me?
And also I'd like to know how the Gonnet matrix works.... Thank you in anticipate
I use ClustalX 1.81 but I don't know if is better to use PAM matrix or BLOSUM matrix.
Can anyone help me?
And also I'd like to know how the Gonnet matrix works.... Thank you in anticipate
Hi
BLAST by Korf, Yandell and Bedell may be of some use to you. Published by O'Reilly press.
-DPK-