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non-canonical versus canonical DNA segment - (Dec/13/2005 )

Can someone please tell me what is the difference of non-canonical and canonical DNA segments? I have searched for in the net, but have not got any good explanations of these names.

Thank you alot!

-justauser-

Hmm, haven't heard that term used a lot, so I'm not too sure. At first, I thought it was referring to the helix structure (B-form being canonical, as compared to A and Z forms), but from some of the literature it looks like those terms are used more to describe DNA sequences - like if a particular recognition site usually has a very specific sequence, that sequence is refered to as canonical, while any major deviations from that sequence are said to be non-canonical.

Please correct me if I'm totally off base - I'm still not too sure if that's what you're talking about. In what context is it used?

-aaronn-

QUOTE (aaronn @ Dec 14 2005, 10:08 PM)
Hmm, haven't heard that term used a lot, so I'm not too sure. At first, I thought it was referring to the helix structure (B-form being canonical, as compared to A and Z forms), but from some of the literature it looks like those terms are used more to describe DNA sequences - like if a particular recognition site usually has a very specific sequence, that sequence is refered to as canonical, while any major deviations from that sequence are said to be non-canonical.

Please correct me if I'm totally off base - I'm still not too sure if that's what you're talking about. In what context is it used?



Thanks, i think you are right. It is about DNA. wink.gif

-justauser-