Deletion and Insertion Allele - what are they? (Jan/27/2009 )
Came across these terms - but cannot find what they mean. Please, can anyone give me simple explanation.
-Nabi-
Nabi on Jan 27 2009, 06:05 PM said:
Came across these terms - but cannot find what they mean. Please, can anyone give me simple explanation.
I am unable to find the reply. Can anyone suggest me any site where I can make my self familiar with basic terminologies in molecular biology like 'deletion allele'

-Nabi-
well it means what it says.
Some alleles of genes are dues to short DNA sequence insertion and deletions into an exon.
Google this paper for an example
A 45-bp Insertion/Deletion Polymorphism of Uncoupling Protein 2 in Relation to Obesity in Tongans
-perneseblue-
Thank U pernesblue. Had come across other papers telling about deletion alleles of ACE in Japanese also. Wish could understand. Will try fresh tomorrow.
I was trying to understand what it meant by deletion allele and wild type allele in knockout mice.
-Nabi-