New technology allows control of gene therapy doses - (Dec/24/2019 )
This describes a virally delivered ribozyme modulated by a Morpholino oligo.
Press release
https://www.eurekalert.org/pub_releases/2019-12/sri-nta122419.php
Primary paper
https://www.gene-tools.com/content/reversible-rna-switch-using-vivo-morpholino-controls-gene-expression-aav-delivered
-Jon Moulton-
Giuseppe Ronzitti. Let’s switch on AAV! Sci Transl Med. 2020;12(579) doi:10.1126/scitranslmed.aba9016 (editorial) https://stm.sciencemag.org/content/12/529/eaba9016
-Jon Moulton-