Protocol Online logo
Top : New Forum Archives (2009-): : Molecular Biology

PROTOCOL FOR LINEARIZED DNA - (Nov/26/2015 )

   I want to linearize my plasmid so i will be able to transfect it 

The enzyme that i will use is Notl 

 

anyone have experience with such protocol?

 

10X

-pana-

Basically mix the DNA with the appropriate restriction buffer and enzyme in a final volume of 50 ul. Digest for 1 hour at 37. Check digest has worked by running on gel. Purify DNA and use for transfection.

-bob1-