miRNA-meditated miRNA suppression? - (Apr/12/2015 )
Hello everyone,
I was wondering if it is possible to downregulate a specific miRNAs using an miRNA?
(sorry if question seems stupid to some, I am not in the field and need to know this as part of my brainstorming for a project)
-redoxrxn-
miRNAs suppress translation. Perhaps you could suppress translation of a transcription factor that regulates transcription of an miRNA. Alternatively, an miRNA completely complementary to a different miRNA could trigger cleavage by Argonaute of that different miRNA's transcript.
-Jon Moulton-