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His-tag and GST-tag - (Nov/15/2013 )

Does anyone know why we cannot use glutathione bead to pull down His-tagged protein while glutatione can be used for GST-tagged?

 

thanks !

-weilun-

GST (Glutathione S-transferase) reacts specifically with glutathione and a Histidine tag does not.

-Missle-