Adenovirus for protease inhibitor studies. - (Jan/22/2013 )
Hi
I am trying to test HCV protease inhibitor on NS3 protein expressed in adenovirus vector. I discovered lately that adenovirus has AVP(cysteine protease) which has charcters similar to NS3 protease, do you think this will interfere with my results?
-bluebird-
Depending on the variant of Ad you use, the cys-protease may have been deleted. You could try expressing the NS3 off a plasmid?
-bob1-