The Differences Between CHO DG44 and CHO dhfr- - (Jun/12/2012 )
I am looking to purchase DG44 cells because these are the cells that I see appear in the literature most often for transient transfection and recombinant protein production for commercial uses. I know that DG44 cells are dhfr- mutants, but the only vendor I see refer to their cells as DG44 is at Invitrogen. All other cell line vendors just refer to them as CHO dhfr-. Is there an actual difference do you think between cells designated DG44 and those designated CHO dhfr-? Thanks!
-chan8-
It seems that they are probably the same cell line - Urlaub and Chasin seem to be the names mentioned with them, and they were at least collaborators on the paper describing a DHFR- CHO cell line.
-bob1-