Alternatives to benzonase? - (Feb/24/2012 )

Hi All,

I'm currently undertaking a purification protocol that requires the use of fairly large amounts of benzonase as my protein is quite contaminated with nucleic acid. As benzonase is not the cheapest reagent I was wondering if anyone was aware of any generic alternative nucleases that might proivde a cheaper alternative.

Thanks for your help.

Iiyama

A member of our lab simply treats her purified protin with DNAse to remove DNA.. Works fine for her and is pretty cheap

http://www.roche-applied-science.com/proddata/gpip/3_6_14_6_1_3.html