Solvents other than DMSO - (Feb/16/2012 )

Hello All,

I am new here and I come here with an issue I am facing with the drugs (inhibitors) I am using.
I have realized that the drugs I use are soluble only in DMSO. However, I am seeing an effect of DMSO in my control lane for the solvent. I try to keep the DMSO concentration at 0.1% but I wish somehow I had another solvent I could use instead of DMSO.
Do you guys have any suggestions in this matter? Are there any solvents that are better for biological use?
Thanks so much in advance!!

DMF
isopropanol
methanol
ethanol

I have forgotten beta-cyclodextrin and hydroxy-propyl-beta-cyclodextrin

water


....
list goes on. Really depends on what chemical you have. Best to refer to the data sheet or MSDS - most of them tell you what solvent to use and in what concentration very clearly. If in any doubt, call the tech department.