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Wacky BioAnalyzer Results - (Jan/04/2012 )

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could be due to genomic DNA contamination that causes rise and fall in baselines ...prefered in line 7-11. These baseline inregularities are due to the presence of longer ssDNA fragments of gDNA.

How did you isolate your RNA? ...is a gDNA contamination possible? Have you run your sample on a agarose gel before?

Regards,
p

-pDNA-

If you had problems to get a good ladder profile, than you got a general problem.
Your ladder profile sugest some problems in the gel, or the pressure.

Next idea: The Syringe clip should be the upper position (Nano and Pico Chips)

-DRYTCYV-

Yep, the clip is in the upper position. I was concerned that pressure may the issue, but when the clip is released , the plunger shoots back up past the 0.9 marker before i gently pull it the rest of the way up.

-RueTheDay-
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