ten broek tissue grinder - (Jan/17/2011 )

Hi,

does someone have some experience with the ten broek tissue grinder?
I need to homogenize biopsies from colonoscopies for RNA isolation. Because of the rigidity and the small size of the tissue we had problems with homogenizing. I found the tissue grinder and thought it might be good for my purpose. Does anyone have any experience with it? Or can you give me advice how to best homogenize the tissue without losing the RNA?


Thanks

i haven't used a ten broek grinder but i would think that if the tissue is that tough that you would want to use a grinder with a pestle that you could motorize (ie-metal shaft). having used manual and motorized grinders, i would definitely recommend motorized where possible (and even then it's not always easy).