Undergrauate's new idea on the dust mites - Please have a look,waiting any suggestions.. (Jan/27/2010 )
from the last post, i find the Consulting here without a specific idea is in vain. 
but, now i really have a idea.
I’m suffering both Rhinitis and Asthma which are both caused by Asthma. And actually dust mites and their wastes is one of the most important reason for causing asthma symptoms. I googled these relevant information, thus found that there is still no efficient biological methods to deal with but only some physical avoidances or chemical spray with side effects. That let me think of the classic example of Bacillus thuringiensis’s toxin expression. Thus, are these any possibilities to find out a specific kind of microorganism whose toxin is aimed at dust mites and their expression can be very high thus delivering sufficient dosage to the targets? Ideally, the toxin is not harmful to the humans or other creatures just as Thuringiensis … and then mass production….working as green additives in the aerosol spray …….
The institution I’m now studying is focused on microbiology (Microbial metallurgy in the mineral processing, Environmental microbiology and Industrial microbiology….). It seems that I should contact and consult my professors to make sure if facilities may be used in this research are available after this winter holiday….
But, before doing that I suppose that I can get every valuable suggestions as well as more knowledge about this topic right here in this forum. Thus my idea could be not that childish when talking with profeesor.
Or could you give any suggestions to narrow the range in order to make my plan more suitable for me ….
By the way, if it is possible, I’ll soon organize a three-member group with my mates. Then applying to my university or government for funds support. Usually, money support would be around 1000~1500 dollars with the during time limitation of 1 year. Again, I have no ambition to fully realize this idea, and the precious experiences I will probably get during the process of the research will be enough…..
Li from China.
oooooh... typing in English is really a tough work that use me 2 and half hours for the words above..... 
There are a lot of viruses (e.g. baculovirus), fungi (e.g. Entomophthora spp., Pandora spp., Verticillium spp., Trichoderma spp., Metarhizium spp., Beauveria spp.) and bacteria (e.g. Bacillus spp.,Pseudomonas spp., Serratia ssp., ) with insecticidal action (or components of them with insecticidal action as the Cry proteins in B.t.).
Anyway the question is, if it works on mites, i.e. if there is also acaricide action or not. With B.t. and its different subspecies that work against quite defined groups of insects (for example B.t. kurstaki against butterfly larvae, B.t tenebrionis against grubs, B.t. israelensis against mosquito larvae) I guess it will be difficult to find any miticide subspecies.
But there are lots of other micro-organisms that might work against mites. Another obstacle might be that the user/buyer finally don't want such stuff in his home and furniture, because it's gross, making a mess or just too difficult and laborious to use. Or the dust mites are too well protected and sheltered in furniture to have a sufficient effect of the active components.
Anyway I'd first do a literature review if there are known micro-organisms/formulations that work against mites, too...."Abamectin" is perhaps a starting point.
Forgot: Consumer/user health is also a point to have a look at, Abamectin might be hazardous to humans, not sure about that.
hobglobin on Jan 28 2010, 06:35 PM said: hobglobin on Jan 28 2010, 06:35 PM said:
yeah, that's still a initial idea, "user/buyer" is not what i suppose to think for the moment.
Forgot: Consumer/user health is also a point to have a look at, Abamectin might be hazardous to humans, not sure about that.
I googled to find that Abamectin(what I have no idea on it before) is really a good insecticide to control insect and mite pests, but still has the growing problem on the resistance to abamectin based antihelmintics and very likely to be harmful to the humans or other creatures.
Still, do you think it's feasible to find out a new sustance from the microorgism which may have less side effet and no resistance to the dust mites...??
All insecticides and acaricides have side effects....from really toxic to vertebrates to perhaps eliciting hypersensitivities...
And also against all regularly used compounds resistances will develop, if not measures are taken against it (as with antibiotics). E.g., even against B.t. crops resistance develops already.
IMO it will be very difficult or impossible for an undergraduate project to find new compounds that have all the qualities you want...it's a job for big companies, that screen millions of such compounds in automated screening processes.
You can try to find additional effects of known compounds against dust mites (as far as the companies didn't do that, but they don't publish their results), find a suitable or improve the formulation (in such agents often a crucial step), or find additional subspecies/serotypes of known bacteria/fungi that might have an effect on dust mites. Actually except avermectins (a group of compounds), I don't know any substances or bacteria that work against mites. Beauveria bassiana and Metarizium anisopliae are used against ticks, perhaps that might work?
B.t. subspecies might work, too (even if I wrote the opposite above ), there seem a lot more in the soil and need to be characterised...I just learnt that there is a subspecies that is effective against snails... 
thank you 
any other suggestions...............any one will be highly appreciated~~