Product Name | c-Myc (N-term) |
Product Page | Visit the Product |
Product Description | Oncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors, the N-Myc gene in neuroblastomas (1), and the L-Myc gene in human small cell lung carcinomas (2). c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 (3) and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription (3). |
Product Manual | Read Product Manual |
Price | $250.00 |
Specification | 100ul |
Product Review | 0 |
Vendor Information | Epitomics https://www.epitomics.com/products/index.php 863 Mitten Road, Suite 103 Burlingame CA 94010 USA Phone: (877) 772-2622 Fax: (650) 583-6680 E-Mail: Rabmabs@epitomics.com |