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Product Name | UB2D1 Polyclonal Antibody |
Product Page | Visit the Product |
Product Description | "UBE2D1 (Ubiquitin Conjugating Enzyme E2 D1) is a Protein Coding gene. Diseases associated with UBE2D1 include Hemochromatosis and Hypoxia. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Ovarian tumor domain proteases. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for UBE2D1." |
Product Manual | Read Product Manual |
Price | $100 |
Specification | 30μl |
Product Review | 0
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Vendor Information | ![]() Abbkine Scientific https://www.abbkine.com Bldg 1, Harbour of Technology Times, No.35, Optical Valley Ave Wuhan Hubei 430074 China Phone: +86-27-59716789 Fax: +86-27-59716788 E-Mail: service@abbkine.com |