BioProduct : Immunology : Antibodies : Secondary Antibodies : SMC1 (phospho Ser966) Polyclonal Antibody

Product Name	SMC1 (phospho Ser966) Polyclonal Antibody
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Product Description	"Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. SMC1A（structural maintenance of chromosomes 1A), which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in SMC1A result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms."
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Price	$220
Specification	100μl
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Vendor Information	Abbkine Scientific  https://www.abbkine.com Bldg 1, Harbour of Technology Times, No.35, Optical Valley Ave Wuhan Hubei 430074 China Phone: +86-27-59716789 Fax: +86-27-59716788 E-Mail: service@abbkine.com