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BioProduct : Protein Chemistry : Recombinant Proteins : Recombinant DKK1 Protein
| Product Name | Recombinant DKK1 Protein |
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| Product Description | Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. |
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| Vendor Information |  Beta Lifescicence https://www.betalifesci.com/ 277 Fairfield Road Fairfield New Jersey 07004 United States Phone: 201-888-7983 E-Mail: info@betalifesci.com |