BioProduct : Immunology : Antibodies : Secondary Antibodies : PTN13 Polyclonal Antibody
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Product Name PTN13 Polyclonal Antibody
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Product Description "Protein Tyrosine Phosphatase, Non-Receptor Type 13 encoded by PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. "
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Price $100
Specification30μl
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Vendor Information
Abbkine Scientific 
https://www.abbkine.com
Bldg 1, Harbour of Technology Times, No.35, Optical Valley Ave
Wuhan
Hubei 430074
China

Phone: +86-27-59716789
Fax: +86-27-59716788
E-Mail: service@abbkine.com