BioProduct : Immunology : Antibodies : Secondary Antibodies : PTEN (phospho Ser380) Polyclonal Antibody
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Product Name PTEN (phospho Ser380) Polyclonal Antibody
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Product Description "PTEN (phosphatase and tensin homologue deleted on chromosome ten), also referred to as MMAC (mutated in multiple advanced cancers) phosphatase, is a tumor suppressor implicated in a wide variety of human cancers. PTEN encodes a 403 amino acid polypeptide originally described as a dual-specificity protein phosphatase . The main substrates of PTEN are inositol phospholipids generated by the activation of the phosphoinositide 3-kinase (PI3K) . PTEN is a major negative regulator of the PI3K/Akt signaling pathway . PTEN possesses a carboxy-terminal, noncatalytic regulatory domain with three phosphorylation sites (Ser380, Thr382, and Thr383) that regulate PTEN stability and may affect its biological activity . PTEN regulates p53 protein levels and activity and is involved in G protein-coupled signaling during chemotaxis ."
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Price $220
Specification100μl
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Vendor Information
Abbkine Scientific 
https://www.abbkine.com
Bldg 1, Harbour of Technology Times, No.35, Optical Valley Ave
Wuhan
Hubei 430074
China

Phone: +86-27-59716789
Fax: +86-27-59716788
E-Mail: service@abbkine.com