BioProduct : Immunology : Antibodies : Secondary Antibodies : PKA IIα reg Polyclonal Antibody
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Product Name PKA IIα reg Polyclonal Antibody
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Product Description "cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by PRKAR2A(protein kinase cAMP-dependent type II regulatory subunit alpha) is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER)."
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Price $220
Specification100μl
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Vendor Information
Abbkine Scientific 
https://www.abbkine.com
Bldg 1, Harbour of Technology Times, No.35, Optical Valley Ave
Wuhan
Hubei 430074
China

Phone: +86-27-59716789
Fax: +86-27-59716788
E-Mail: service@abbkine.com