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BioProduct : Immunology : Immunohistochemistry Reagents : HER2 : ErbB2
| Product Name | HER2 / ErbB2 |
| Product Page | Visit the Product |
| Product Description | HER2 / ErbB2 is one of the four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases (1). The kinase activity of ErbB2 can be activated without ligand if it is overexpressed, and by association with other ErbB proteins (2). Overexpression of ErbB2 is detected in almost 40% of human breast cancers (3). Binding of c-Cbl ubiquitin ligase to Tyr1112 of ErbB2 leads to poly-ubiquitination of ErbB2 and enhances its degradation (4). ErbB2 is one of the major targets for the treatment of breast cancer and other carcinomas. |
| Product Manual | Read Product Manual |
| Price | $250.00 |
| Specification | 100ul |
| Product Review | 0
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| Vendor Information |  Epitomics https://www.epitomics.com/products/index.php 863 Mitten Road, Suite 103 Burlingame CA 94010 USA Phone: (877) 772-2622 Fax: (650) 583-6680 E-Mail: Rabmabs@epitomics.com |