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BioProduct : Immunology : Antibodies : Secondary Antibodies : Dok-3 Polyclonal Antibody
| Product Name | Dok-3 Polyclonal Antibody |
| Product Page | Visit the Product |
| Product Description | "Dok-1, Dok-2 and Dok-3 are members of a class of ""docking"" proteins which contain multiple tyrosine residues and putative SH2 binding sites. Dok-1 associates with the Ras GTPase activating protein (Ras GAP) upon tyrosine phosphorylation. Dok-2 (also designated p56 Dok) has also been identified as a potential mediator of the effects of p210 Bcr-Abl.Dok-3 is an adapter involved in the recruitment of inhibitory molecules and is highly expressed in B cells and macrophages.Immunoreceptor-mediated cellular activation induces tyrosine phosphorylation of Dok-3.Upon phosphorylation, Dok-3 binds to 5' inositol phosphatase SHIP and the protein tyrosine kinase Csk.Dok-3 may play a significant role in the negative regulation of immunoreceptor signaling in hemopoietic cells." |
| Product Manual | Read Product Manual |
| Price | $360 |
| Specification | 200μl |
| Product Review | 0
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| Vendor Information |  Abbkine Scientific https://www.abbkine.com Bldg 1, Harbour of Technology Times, No.35, Optical Valley Ave Wuhan Hubei 430074 China Phone: +86-27-59716789 Fax: +86-27-59716788 E-Mail: service@abbkine.com |