BioProduct : Immunology : Antibodies : Secondary Antibodies : DNA Ligase IV (phospho Thr650) Polyclonal Antibody
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Product Name DNA Ligase IV (phospho Thr650) Polyclonal Antibody
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Product Description "The protein encoded by LIG4 is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. "
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Price $220
Specification100μl
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Vendor Information
Abbkine Scientific 
https://www.abbkine.com
Bldg 1, Harbour of Technology Times, No.35, Optical Valley Ave
Wuhan
Hubei 430074
China

Phone: +86-27-59716789
Fax: +86-27-59716788
E-Mail: service@abbkine.com