BioProduct : Immunology : Antibodies : Secondary Antibodies : Cleaved-Factor B Bb (K260) Polyclonal Antibody
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Product Name Cleaved-Factor B Bb (K260) Polyclonal Antibody
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Product Description "CFB（complement factor B) encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. CFB localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in CFB are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of CFB is 421 bp from the 5' end of the gene for complement component 2. "
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Price $360
Specification200μl
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Vendor Information
Abbkine Scientific 
https://www.abbkine.com
Bldg 1, Harbour of Technology Times, No.35, Optical Valley Ave
Wuhan
Hubei 430074
China

Phone: +86-27-59716789
Fax: +86-27-59716788
E-Mail: service@abbkine.com