BioProduct : Immunology : Antibodies : Secondary Antibodies : CaVα2δ2 Polyclonal Antibody
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Product Name CaVα2δ2 Polyclonal Antibody
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Product Description "Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. CACNA2D2 (calcium voltage-gated channel auxiliary subunit alpha2delta 2)encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by CACNA2D2 undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in CACNA2D2 are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in CACNA2D2 are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms."
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Price $100
Specification30μl
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Vendor Information
Abbkine Scientific 
https://www.abbkine.com
Bldg 1, Harbour of Technology Times, No.35, Optical Valley Ave
Wuhan
Hubei 430074
China

Phone: +86-27-59716789
Fax: +86-27-59716788
E-Mail: service@abbkine.com