Product Name | Protein A Sepharose |
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Product Description | "The origin of protein A is from the bacteria Staphylococcus aureus. Protein A is capable of binding most classes and subclasses of immunoglobulins from Goat, Rabbit, Mouse and Human. Our Protein A beads are produced using genetically engineered form of Protein A. Nonessential regions have been removed while leaving the immunoglobulins binding sites intact. The recombinant Protein A has been immobilized to Sepharose beads using our TargetLock chemistry, in order to create a winner product for the affinity purification and immunoprecipitation of various mammalian immunoglobulins. Protein A beads are being routinely used for the isolation of IgG from several species of mammals. The binding of Protein A to IgGs vary between animal species and between IgG subclasses within the same species. Major limitation of protein A lies with the weak binding it presents towards mouse IgG1-a common IgG subclass. Despite that, Protein A possesses useful properties that make it a popular choice for the isolation of most types of IgGs. Protein A binds IgGs through the Fc region of the molecules leaving the Fab region available for binding the antigen. Protein A Beads are commomnly used for antibodies purification and for the isolation of immune complexes by Immunoprecipitation (IP)." |
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Price | |
Specification | 5 ml |
Product Review | 0 |
Vendor Information | Europa Bioproducts Ltd http://europa-bioproducts.com 15-17 North Street Ely Cambrideshire CB7 5XW United Kingdom E-Mail: info@europa-bioproducts.com |