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Rac1 mutants - (Mar/08/2009 )

Hi,

I'm would like to know what kind of amino acid mutations to the following RAC1 constitutively active and dominant negative mutants have:

1) RAC1 V12: constitutively active
2) RAC1 17N: dominat negative

All websites just describe theri function and not what aa change?
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-SF_HK-

SF_HK on Mar 8 2009, 07:45 PM said:

Hi,

I'm would like to know what kind of amino acid mutations to the following RAC1 constitutively active and dominant negative mutants have:

1) RAC1 V12: constitutively active
2) RAC1 17N: dominat negative

All websites just describe theri function and not what aa change?


Doesn't it mean that the 12th or 17th aa is mutated to V or N?

-WHR-