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Top : New Forum Archives (2009-): : DNA Methylation and Epigenetics

epigenetics and heridity - (Mar/27/2011 )

What makes epigenetics a heritable trait? Is it imprinting and x-inactivation? Can histone changes also be passed on from one generation to the next.

-Boba-

During DNA replication epigenetic marks (i.e.-histone modifications) are preserved by keeping some histones associated with the replication template. I think CAF-1 and maybe ASF-1 histone chaperones mediate this, but i'm not 100% certain.

-chabraha-